The Metabolic Effects of Caffeine and How This Effects Physical Activity


This paper seeks to explore the metabolic effects of caffeine and examines further how it affects the physical activities of the body. Caffeine’s impact on the body as well as the metabolic activity for the drug will have its conclusions drawn from the experiments which will be done. Further, the effects of caffeine are evaluated both on the negative and positive side. This is because the effects of campaign vary from individual to individual as well as the different contexts when taken. Thus, this paper seeks to establish the details regarding the metabolic activity of caffeine as well as its detailed effect of physical activities in the body of an individual.

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Caffeine is consumed by a large number of people due to its presence in most beverages like tea, coffee and chocolate. The effects of caffeine range from beneficial to harmful based on the rate of consumption by different persons. When consumed moderately, caffeine has the positive effect of increasing the mental activity as well as physical capability of the user. Prolonged consumption of caffeine leads to addiction of the drug. Thus, when not consumed by aspects of physical activity as well as mental activity will be affected since the individual cannot function normally without consuming the drug (Dohert and Smith 7; Heickmann, Weil and Meija 5).

Review Sections

1. Experiment I

The main purpose of this research paper is to test the claims of enhanced athlete performance and voluntary exercise behaviour for selected soft drinks (red bull and Gatorade) on a unique animal breed; specific high runner line of mice.

2. Experiment 2

The main purpose of this research study is to use the meta-analytic approach in examining the effects of caffeine ingestion on ratings of perceived exertion.

3. Experiment 3

The main purpose of this research study is to examine the stimulant effects of caffeine on the locomotor behaviour of mice and how they are mediated through the blockade of adenosine

Methonds and Materials

1. Experiment 1 and Experiment 2

Sixty-three (63) female breeders of high runner were chosen to participate in the experiment. All the mice were exposed to water, caffeine as well as the ‘sports drink’. The stimulation effect of both the mice was measured through the number of revolutions that were made by the mice upon exposure to the three fluids.

2. Experiment 3

Mice of High runner life were also selected for the experiment. They were placed on the light so that their revolution was measured during the light hours. This was the sole reason that their revolution seemed to be high during the night on the wheels as compared to day-time. This group of mice was also exposed to the drinks of caffeine; water as well as ‘sports drink’ after which exposure to VO2 max was done after a few days (Daniel and Kot 8).


For experiments one and two, it was evident that the red bull drink was consumed more as compared to the ‘sports drink’. For experiment three, upon exposure to the three drinks, it was evident that the highest consumed drinks were those with caffeine (Red Bull and caffeine). The least of the drinks consumed were water and taurine. It was further noted that the amount of revolutions also increased with the exposure to caffeine. This indicated stimulation on the side of the high runner mice on the wheel (Malika, Catherine, Menard and Vaugeis 5; Terry, Battram, El-Sohemy and Thong 4; Keffi, Bhatti and Patil 3).

Further, caffeine also known to contain the sodium and potassium ion enable the hyperactivity of caffeine when taken by an individual or even upon exposure by animal say mice. The mice were revolving around the wheel at high speed upon exposure to caffeine than exposure to the other drinks in the experiment (Keffi, Batti and Patil 4.) Additionally, it is of essence to note that the hyperactivity of the mice upon their revolution on the wheels is as a result of the stimulation of the central nervous system of the organisms in context (mice). Upon this stimulation, the mice are able to do more revolution because of the high arousal level of the adenosine (Terry, Battram, El-Sohemy and Thong 5).


Caffeine still remains the used drug by most people even though the effects are split; both negative and positive. Besides, considering the positive effects; caffeine offers both negative and, positive stimulation, prevents cancerous diseases as well as prevents the Parkinson’s disease. On the contrary, the negative effects of caffeine include: sleeplessness, anxiousness and cases of pregnancy failure. The rate of metabolism of caffeine differs from individual to individual. For instance, expectant women as well as persons with liver disorder tend to have a lower metabolism rate for caffeine. Moreover, smokers have higher metabolic rates of caffeine as compared to persons who do not smoke (Kim, Shin, Beom, Min and Yang 1; Shearer and Graham 2; Davis and Green 890-893).


Works Cited

Daniel Wladlywa and Kot Marta. Caffeine as a Marker Substrate for Testing Cytochrome P450 Activity in Human and Rat. Polish Academy of Sciences. 2008.

Davis and Green. Caffeine and Anaerobic Performance. USA: University of North Albama. 2009

Doherty, M. and Smith, T.H. Effects of Caffeine Ingestion on Ratings of Perceived Exertion during and After Exercise. Scandinavian Journal of Medicine and Science in Sports. Vol. 15, pp: 65-68. 2005.

Graham Terry, Daniella Battram, Flemming Della, Ahmed El-Sohemy and Farah Thong. Does Caffeine Alter Muscle Carbohydrate and Fat Metabolism During Exercise? NRC Research Press. 2008.

Jane Shearer and Terry Graham. Performance Effects and Metabolic Consequences of Caffeine and Caffeinated Energy Drinks Consumption on Glucose. Nutritional Reviews. 2014.

James Keffe, Sahlman Bhatti and Harshal Patil. Effects of Habitual Coffee Consumption on Cardiometric Disease, Cardiovascular Health and all Course Mortality. JACC. 2013.

Mellnie Heckman, Jorje Weil and Elvira Weija. Caffeine In Foods. A Comprehensive Consumption, Functionality, Safety and Regulatory Matters. Institute of Food Technologist. 2010.

Tae-Wook Kim, Young-Oh Shin, Jeon-Beom Lee, Young-Ki Min and Hung-Mo Yan. Effect of caffeine on the metabolic responses of lipolysis and activated sweat gland density in human during physical activity. Food Science and Biotechnology. Vol.9 (4).Pp: 1077-1081. 2010.

Yacoubi El Malika, Ledent Catherine, Menard Jean-Francaise and Vaugeis Jean-Marie. The Stimulant Effects of Caffeine on Locomotor Behaviour in Mice are mediated